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Dr. Juan Hou, Ph.D, MD
Research Associate
Terry Fox Laboratory

Contact information:
Phone: (604)-675-8000 ext: 7724
Fax:
(604) 877-0172
E-mail: jhou@bccrc.ca

Dr. Juan Hou, received her MD from Beihua University, Jilin City, Jilin, China. She obtained a PhD in Developmental Biology from Osaka University, Japan, under the supervision of Dr Hiroshi Hamada. Her graduate work focused on left-right patterning in early mouse embryogenesis. Then she joined Pamela Hoodless Laboratory as a Post-Doctoral Fellow in 2004, working on endoderm formation and patterning. Through this study, she identified several definitive endoderm specific genes, which now are being widely contributed to the endoderm field. In addition to endoderm development, one of her most recent research interests is early placenta development. 

 

Publications:

Hou J, Hoodless PA. (Updated August 4, 2010). Foxh1 (Mus musculus, Homo sapiens). From the Transcription Factor Encyclopedia, http://www.cisreg.ca/tfe. Accessed March 22, 2011. Hassan AS, Hou J, Wei W, Hoodless PA, Expression of two novel transcripts in the mouse definitive endoderm. Gene Expr Patterns 10:127-134, 2010. Hassan AS, Hou J, Wei W, Hoodless PA, Expression of two novel transcripts in the mouse definitive endoderm. Gene Expr Patterns 10:127-134,

Hassan AS, Hou J, Wei W, Hoodless PA. Expression of two novel transcripts in the mouse definitive endoderm. Gene Expr Patterns 10:127-134, 2010. View Abstract

McKnight K*, Hou J*, Hoodless PA. FoxH1 and FoxA2 are not required for formation of the midgut and hindgut definitive endoderm. Dev Biol 337: 471-481, 2010. View Abstract
(*Co-first authors)

McKnight K, Hou J, Hoodless PA. Dynamic expression of thyrotropin-releasing hormone in the mouse definitive endoderm. Dev Dyn 236 (10): 2009-17, 2007.  View Abstract

Hou J, Charters AM, Lee SC, Zhao Y, Wu MK, Jones SJ, Marra MA, Hoodless PA. A systematic screen for genes expressed in definitive endoderm by Serial Analysis of Gene Expression (SAGE). BMC Dev Biol 7:92, 2007. Highly Accessed. View Abstract

Siddiqui A, Khattra J, Delaney A, Zhao Y, Astell C, Asano J, Babakaiff R, Barber S, Beland J, Bohacec S, Brown-John M, Chand S, Charters AM, Cullum R, Dhalla N, Featherstone R, Gerhard DS, Hoffman B, Holt R, Hou J, Kuo BY-L, Lee LLC, Lee S, Leung D, Ma K, Matsuo C, Mayo M, McDonald H, Prabhu A-L, Pandoh P, Riggins GJ, Ruiz de Algara T, Smailus D, Stott J, Tsai M, Varhol R, Vrljicak P, Wong D, Wu MK, Xie Y-Y, Yang G, Zhang I, Hirst M, Jones SJM, Helgason CD, Simpson EM, Hoodless PA & Marra M. A mouse atlas of gene expression: A public, large-scale, digital gene expression profiling resource from precisely defined developing C57BL/6J mouse tissue and cells. Proc Natl Acad Sci USA 102(51): 18485-90, 2005. This paper was listed as one of the "top 20" most viewed papers in PNAS. View Abstract

Hou J, Yashiro K, Okazaki Y, Saijoh Y, Hayashizaki Y,Hamada H. Identification of a novel left-right asymmetrically-expressed gene in the mouse belonging to the BPI/PLUNC superfamily. Dev Dyn. 229(2): 373-9, 2004. View Abstract

Sakuma R, Ohnishi  Y, Meno C, Fujii H, Hou J, Takeuchi J, Ogura T, Li E, Miyazono K, Hamada H. Inhibition of nodal signalling by Lefty mediated through interaction with common receptors and efficient diffusion. Genes Cell 7(4): 401-412, 2002. View Abstract

Hou J, Hamada H. Roles of nodal-lefty regulatory loops in embryonic patterning of vertebrates. Genes Cell 6:923-930, 2001. Review. View Abstract

 

 

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