Patricia (Patty) Rosten
Research Assistant

Ji J, Risueno RM, Hong S, Allan D, Rosten P, Humphries K & Bhatia M. Ectopic expression of Nup98-HoxA10 augments erythroid differentiation of human embryonic stem cells. Stem Cells 29:736-741, 2011.

Sekulovic S, Gasparetto M, Lecault V, Hoesli CA, Kent DG, Rosten P, Wan A, Brookes C, Hansen CL, Piret JM, Smith C, Eaves CJ & Humphries RK. Ontogeny stage-independent and high-level clonal expansion in-vitro of mouse hematopoietic stem cells stimulated by an engineered NUP98-HOX fusion transcription factor. Blood 118:4366-4376, 2011.

Argiropoulos B, Yung E, Xiang P, Lo CY, Kuchenbauer F, Palmqvist L, Reindl C, Heuser M, Sekulovic S, Rosten P, Muranyi A, Goh S-L, Featherstone M & Humphries RK. Linkage of the potent leukemogenic activity of Meis1 to cell cycle entry and transcriptional regulation of cyclin D3. Blood 115:4071-82, 2010.

Gurevich RM, Rosten PM, Schwieger M, Stocking C & Humphries RK. Retroviral integration site analysis identifies ICSBP as a collaborating tumor suppressor gene in NUP98-TOP1-induced leukemia. Exp Hematol 34:1192-1201, 2006.

Schessl C, Rawat VP, Cusan M, Deshpande A, Kohl TM, Rosten PM, Spiekermann K, Humphries RK, Schnittger S, Kern W, Hiddemann W, Quintanilla-Martinez L, Bohlander SK, Feuring-Buske M & Buske C. The AML1-ETO fusion gene and the FLT3 length mutation collaborate in inducing acute leukemia in mice. J Clin Invest 115:2159-2168, 2005.

Imren S, Fabry ME, Westerman KA, Pawliuk R, Tang P, Rosten PM, Nagel RL, Leboulch P, Eaves CJ & Humphries RK. High-level b-globin expression and preferred intragenic integration after lentiviral transduction of human cord blood stem cells. J Clin Invest 114:953-962, 2004.

Pineault N, Buske C, Feuring-Buske M, Abramovich C, Rosten P, Hogge DE, Aplan PD & Humphries RK. Induction of acute myeloid leukemia in mice by the human leukemia-specific fusion gene NUP98-HOXD13 in concert with Meis1. Blood 101:4529-4538, 2003.

Buske C, Feuring-Buske M, Antonchuk J, Rosten P, Hogge DE, Eaves CJ & Humphries RK. Overexpression of HOXA10 perturbs human lymphomyelopoiesis in vitro and in vivo. Blood 97:2286-2292, 2001.

Krystal G, Damen JE, Helgason CD, Huber M, Hughes MR, Kalesnikoff J, Lam V, Rosten P, Ware MD, Yew S & Humphries RK. SHIPS ahoy. Int J Biochem Cell Biol 31:1007-1010, 1999.

Helgason CD, Damen JE, Rosten P, Grewal R, Sorensen P, Chappel SM, Borowski A, Jirik F, Krystal G & Humphries RK. Targeted disruption of SHIP leads to hemopoietic perturbations, lung pathology, and a shortened life span. Genes Dev 12:1610-1620, 1998.

Damen JE, Liu L, Wakao H, Miyajima A, Rosten P, Jefferson AB, Majerus PW, Krosl J, Humphries RK & Krystal G. The role of erythropoietin receptor-tyrosine phosphorylation in erythropoietin-induced proliferation. Leukemia 11:423-425, 1997.

Damen JE, Liu L, Rosten P, Humphries RK, Jefferson AB, Majerus PW & Krystal G. The 145-kDa protein induced to associate with Shc by multiple cytokines is an inositol tetraphosphate and phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase. Proc Natl Acad Sci USA 93:1689-1693, 1996.

Ware MD, Rosten P, Damen JE, Liu L, Humphries RK & Krystal G. Cloning and characterization of the human 145 kDa SHC-associated inositol 5-phosphatase, SHIP. Blood 88:2833-2840, 1996.

Hough MR, Rosten PM, Sexton TL, Kay R & Humphries RK. Mapping of CD24 and homologous sequences to multiple chromosomal loci. Genomics 22:154-161, 1994.

Kay R, Rosten PM & Humphries RK. CD24, a signal transducer modulating B cell activation responses, is a very short peptide with a glycosyl phosphatidylinositol membrane anchor. J Immunol 147:1412-1416, 1991.

Whiting JL, Rosten PM & Chow AW. Determination by western blot (immunoblot) of seroconversions to toxic shock syndrome (TSS) toxin 1 and enterotoxin A, B, or C during infection with TSS- and non-TSS-associated Staphylococcus aureus. Infect Immun 57:231-234, 1989

Rosten PM, Bartlett KH & Chow AW. Purification and purity assessment of toxic shock syndrome toxin 1. Rev Infect Dis. 11 Suppl 1:S110-5; discussion S115-6, 1989.

Rosten PM, Bartlett KH & Chow AW. Serologic responses to toxic shock syndrome (TSS) toxin-1 in menstrual and nonmenstrual TSS. Clin Invest Med 11:187-92, 1988.

Rosten PM, Bartlett KH & Chow AW. Detection and quantitation of toxic shock syndrome toxin 1 in vitro and in vivo by noncompetitive enzyme-linked immunosorbent assay. J Clin Microbiol 25:327-32, 1987.